Pyrimidines And Derivatives
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Filtered Search Results
Aobchem Ethyl 3-(4-bromo-3-methoxyphenyl)-3-hydroxypropanoate | 95% | CAS 2901106-50-9 | C12H15BrO4 | 1g
Ethyl 3-(4-bromo-3-methoxyphenyl)-3-hydroxypropanoate | 95% | CAS 2901106-50-9 | C12H15BrO4 | 1g
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Sigma Aldrich Fine Chemicals Biosciences Guanosine >=98% | 118-00-3 | MFCD00010182 | 25G
Guanosine >=98% | Purity: >=98% | Mol Wt: 283.24 | 118-00-3 | MFCD00010182 | 25G
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Ambeed AMBEED
5000949839 ETHYL 2-PYRIMIDIN-4-YLAC 100MG
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Aobchem 4-(Pyrimidin-2-yloxy)phenylboronic acid pinacol ester | ≥95% | CAS 330792-87-5 | C16H19BN2O3 | 250mg
4-(Pyrimidin-2-yloxy)phenylboronic acid pinacol ester | ≥95% | CAS 330792-87-5 | C16H19BN2O3 | 250mg
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Ambeed AMBEED
5000949425 PYRIMIDIN-2-YLBORONIC ACI 50MG
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Chemscene CHEMSCENE
5000579899 7H-PYRROLO 2 3-D PYRIMIDIN- 5G
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Ambeed AMBEED
5000847184 2- METHYLTHIO PYRIMIDIN 100MG
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eMolecules 51953-18-5 | Pyrimidin-4-ol | Ambeed | MFCD00038024 | 96.089 | C4H4N2O | 97.000 | Oc1ccncn1 | 100g | 570567697
Pyrimidin-4-ol | Ambeed | 51953-18-5 | MFCD00038024 | 96.089 | C4H4N2O | 97.000 | Oc1ccncn1 | 100g | 570567697
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Medchemexpress LLC Methyl 4-[6-[4-(methoxycarbonylamino)phenyl]-4-morpholin-4-ylpyrazolo[3,4-d]pyrimidin-1-yl] | 1062169-56-5 | 98.0% | 25 MG
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WYE-354 is a cell-permeable, ATP-competitive inhibitor of mechanistic target of rapamycin (mTOR) used as a research tool to block signaling through mTORC1 and mTORC2 in cell signaling and oncology studies.
- Potent mTOR inhibition with IC50 ≈ 4-5 nM.
- Cell-permeable small molecule suitable for cellular assays.
- High purity (98.0%) for reproducible results.
- Molecular weight 495.53 g/mol; formula C24H29N7O5.
- White to off-white solid; soluble in DMSO; store powder at -20°C.
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Medchemexpress LLC Urea, N-[4-[4-(4-morpholinyl)-6-(3-oxa-8-azabicyclo[3.2.1]oct-8-yl)-1,3,5-triazin-2-yl]phenyl]-N'-4-pyridinyl | 1197160-28-3 | 98.0% | 488.54 | 100 MG
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PKI-179 is a potent and orally active dual PI3K/mTOR inhibitor, showing anti-tumor activity in vivo. It is for research use only and not sold to patients.
- Potent and orally active dual PI3K/mTOR inhibitor.
- Exhibits activity over E545K and H1047R.
- Inhibits cell proliferation with IC50s of 22 nM for MDA-MB-361 cells and 29 nM for PC-3 cells.
- Good oral bioavailability (98% in nude mouse, 46% in rat, 38% in monkey, and 61% in dog).
- High half-life (>60 min).
- Appearance: Solid, off-white to yellow.
- Shows anti-tumor activity in vivo.
- Well tolerated in nude mice bearing MDA-361 human breast cancer tumors.
- Exhibits pronounced tumor growth arrest when dosed above 10 mg/kg in nude mice.
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Enzo Life Sciences PI-103 (1mg). CAS: 371935-74-9
Potent, cell permeable and ATP-competitive inhibitor of DNA-PK, phosphoinositide 3-kinase (PI(3)K), the rapamycin-sensitive (mTORC1) and rapamycin-insensitive (mTORC2) complexes of the protein kinase mTOR. Exhibits little activity towards a panel of more than 40 other kinases even at concentrations as high as 10µM. Effectively blocks cell proliferation in glioma cell lines both in vitro and in vivo. Alternative name: 3-(4-(4-Morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol. Purity: ≥97% (HPLC). Solubility: Soluble in DMSO (5mg/ml; warm). Long Term Storage: -20°C.
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eMolecules 3114-30-5 | 1-(3,4-DIBROMOPHENYL)ETHANONE | AstaTech | MFCD07780696 | 277.943 | C8H6Br2O | 95.000 | CC(=O)c1ccc(Br)c(Br)c1 | 1g | 268486435
1-(3,4-DIBROMOPHENYL)ETHANONE | AstaTech | 3114-30-5 | MFCD07780696 | 277.943 | C8H6Br2O | 95.000 | CC(=O)c1ccc(Br)c(Br)c1 | 1g | 268486435
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Medchemexpress LLC 1-(pyrimidin-5-yl)ethan-1-ol | 79691-74-0 | 96.6% | 124.14 g·mol⁻¹ | C6H8N2O | 250 MG
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1-(Pyrimidin-5-yl)ethan-1-ol is a pyrimidine-derived small-molecule intermediate used in organic and medicinal chemistry for the synthesis of pyrimidine-containing active compounds. It is supplied as a research-use reagent with documented purity and analytical certification.
- Used as an intermediate in organic and medicinal chemistry syntheses.
- Molecular formula C6H8N2O and molecular weight 124.14 g·mol⁻¹.
- Purity typically 96.6% by HPLC (certificate of analysis available).
- Provided in small milligram-scale quantities suitable for research applications.
- Stored under recommended conditions to preserve stability.
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Selleck Chemical LLC B-Raf IN 1
B-Raf IN 1 is an inhibitor of Raf wih IC50 values of 24 nM and 25 nM for B-Raf and C-Raf respectively It is selective over 13 other kinases including PKC IKK and PI3K
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eMolecules 271-70-5 | 1H-Pyrrolo[2,3-d]pyrimidine | Synthonix - Stock | MFCD08234403 | 119.127 | C6H5N3 | 97.000 | c1cc2cncnc2[nH]1 | 5g | 525922384
1H-Pyrrolo[2,3-d]pyrimidine | Synthonix - Stock | 271-70-5 | MFCD08234403 | 119.127 | C6H5N3 | 97.000 | c1cc2cncnc2[nH]1 | 5g | 525922384
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